Diseases    

The Dimopoulos group investigates vector-borne diseases such as Malaria and Dengue.

Malaria & Dengue


MALARIA
Malaria is transmitted by anopheline mosquitoes and caused by protozoan parasites of the genus Plasmodium. The four species of Plasmodium that can infect humans are Plasmodium falciparum and Plasmodium vivax, Plasmodium ovale and Plasmodium malariae. The two former are the most serious. Symptoms of malaria are fever, chills, and flu-like illness. Severe complications can develop if left untreated. Approximately 515 million cases of malaria occur worldwide each year, and over one million people deaths, mostly young children in sub-Saharan Africa. Bednets, insecticides, and antimalarial drugs are currently employed to fight malaria. However, malaria is a disease of poverty, and is also the cause of poverty; the socioeconomic impact of malaria is vast. Eradication of this disease is therefore expected to lead to major improvements in the endemic areas.

For more information on malaria see:
- http://www.cdc.gov/Malaria/
- http://www.who.int/topics/malaria/en/

      

DENGUE
Dengue fever and dengue hemorrhagic fever are caused by dengue viruses that belong to the Flavivirus genus. Four antigenically distinct serotypes exist (DEN-1, DEN-2, DEN-3, and DEN-4) and infection with one serotypes results in immunity to only that serotype. Dengue viruses are spread by Aedes mosquitoes. The Aedes aegypti is the most common dengue vector while Aedes albopictus is also emerging as a potentially  important vector. The geographic distribution of dengue is similar to malaria but more frequently associated to urban areas because of the vectors capacity to adapt to these man-made environments.

For more information on dengue see:
- http://www.cdc.gov/ncidod/dvbid/dengue/
- http://www.who.int/topics/dengue/en/

For more information on vector-borne diseases see:
- http://www.cdc.gov/ncidod/dvbid/index.html
- http://www.who.int/heli/risks/vectors/vector/en/index.html

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